Biology 4540G

Developmental Genetics 



      

      


      

      


      

      


      

      


      
    		
     This course
      is the application of basic genetic analysis for dissection of
      the process of biological development. The genetics applied to
      this problem are allele classification, genetic screens, epistasis,
      transgenesis and mosaic analysis. The problems in Developmental
      Biology investigated are anterior posterior axis formation in
      Drosophila, morphogen gradients, lateral inhibition, evolution
      of the animal body plan, and genetic analysis of evolutionary
      conservation of developmental pathways. The laboratory component
      of this course will highlight some of the genetic analyses discussed
      in lecture using the Drosophila segmentation gene fushi tarazu
      as the example. Techniques used in the laboratory are cuticle
      preparation, whole mount protein immunolocalization, in situ
      hybridization and reporter gene expression. 
  





Instructor: Dr. Anthony Percival-Smith, Associate
Professor, Department of Biology, UWO. Room #305 Western Science
Center. aperciva@uwo.ca



Teaching Assistant: Elyse Burlingham, Department
of Biology, UWO. Room #361 Western Science Center. eburling@uwo.ca