URL: http://www.nature.com/cgi-taf/DynaPage.taf?file=/nature/journal/v409/n6822/full/409747b0_fs.html
Date accessed: 25 February 2001
Nature 409, 747 (2001) © Macmillan Publishers Ltd.
15 February 2001
ALISON ABBOTT
In an announcement timed to coincide with the publication of the human genome
sequence, a group of top-level proteomics researchers has launched a global
Human Proteome Organisation (HUPO). HUPO's founders see it as a post-genomic analogue of the Human Genome
Organisation (HUGO). Its mission will be to increase awareness of, and support
for, large-scale protein analysis, in scientific, political and financial
circles. HUGO was created in 1988 by publicly funded researchers who wanted to
coordinate global efforts to sequence the genome. Now that the draft human
genome sequence has been published, researchers are turning their attention to
identifying the functions and expression patterns of the proteins encoded by the
genes. It is generally believed that patterns of protein production — the
proteome — will correlate with disease states, which may lead to new
treatments. "Proteins are central to our understanding of cellular function and
disease processes, and without a concerted effort in proteomics, the fruits of
genomics will go unrealized," says Ian Humphery-Smith of the University of
Utrecht in the Netherlands, one of HUPO's founder members. So far, the embryonic HUPO has created a Global Advisory Council to foster
international cooperation, and two regional task-forces in Europe and Japan. An
inaugural meeting will take place in the spring to define detailed objectives
and to elect a president.
Category: 54. Proteomics