50. Gene Therapy, Genetic Research, and Genetically Modified Species
| Date | Source | Title | Summary | Other Categories |
| 05.11.2001 | New York Times | Getting the Athletic Edge May Mean Altering Genes | Concerned that athletes would soon employ genetic engineering, the IOC and the affiliated World Anti-Doping Agency are about to convene inaugural meetings on the subject. The officials will discuss the potential benefits and risks of genetic engineering and the potential detection methods, and they will face a number of ethical questions. | 32. Genome Project and Genomics |
| 01.18.2001 | Nature | A viable herd of genetically uniform cattle | Inbreeding, which can lead to the loss of genetic variation or the accumulation of deleterious alleles, has been shown to reduce fitness in wild, zoo, laboratory and farmed animals. This article demonstrates that when combined with selection, inbreeding may purge deleterious alleles, resulting in a viable herd of cattle that is almost genetically uniform. | |
| 01.12.2001 | Washington Post | Scientists Create First Genetically Altered Monkey | The creation of the world's first genetically altered monkey is a promising sign that soon we will have access to genetically customized primates for medical research. | |
| 01.12.2001 | BBC News | GM monkeys will 'not replace mice' | Scientists have genetically engineered a monkey, the closest relative yet to humans to have its "life code" altered in the laboratory; however, they maintain GM monkeys are unlikely to change the practices in UK labs. Moreover, ethical questions still surround the use of these primates in many scientific studies. | 4. Ethical and Social Issues Arising out of Biotechnology |
| 01.12.2001 | Yahoo!News (Reuters) | Genetic Advances Spark Fears of Science Gone Awry | Using the genetically modified monkey as the starting point of the discussion, this article explores some concerns regarding scientific advances. | 4. Ethical and Social Issues Arising out of Biotechnology, 39. General Issues about Scientific Research |
| 01.12.2001 | Le Monde | Naissance du premier singe transgénique | Scientists in the US have genetically modified a rhesus monkey. "ANDi" is the genetically modified animal nearest to man ever to be designed. Scientists have developed ANDi to research on diseases such as AIDS and breast cancer. They hope the development of transgenetic animals will aid in medical research. | |
| 01.11.2001 | BBC News | Modified monkey poses questions | BBC News Online science editor Dr David Whitehouse considers some of the ethical arguments that are raised by the first GM monkey in this article. Background of the research team that produced the animal is also provided. | 4. Ethical and Social Issues Arising out of Biotechnology |
| 01.02.2001 | Washington Post (Washtech.com) | On the Trail of Rare Diseases | New company specializes in finding genetic mutations in its patients. | |
| 12.2000 | Nature Biotech | Gelsingers, UPenn settle suit | The lawsuit brought by Jesse Gelsinger's family against several gene therapy researchers and administrators at the UPenn was settled early in November. The settlement amount remains confidential, but the university’s serious initiative to improve the conditions under which clinical research is conducted is said to have meant a great deal in resolving this case. The family also dismissed claims against UPenn bioethicist Arthur Caplan and former medical dean William Kelley. | |
| 12.02.2000 | Washington Post | Ignorance Undercuts Gene Tests' Potential | In an increasing number of cases, doctors aren't correctly interpreting genetic test results and aren't counseling patients as to their impact. | 4. Ethical and Social Concerns Arising out of Biotechnology |
| 12.02.2000 | Washington Post | With Doctors, There's No Telling the Future | Doctors don't like giving patients the results of genetic testing and are sometimes overly optimistic as to the impact of those results on their patients. | 4. Ethical and Social Concerns Arising out of Biotechnology |
| 11.23.2000 | Nature | Diabetes: Gene therapy for rats and mice | [Technical] Delivery of an insulin-encoding gene into diabetic rats and mice has helped them to regulate their blood glucose levels; but there are still obstacles to overcome before this approach can be used in humans (i.e. physiological differences). | |
| 11.2000 | Nature Biotech | Gene-therapy death prompts broad civil lawsuit | One year since the death of Jesse Gelsinger in a gene therapy clinical trial at the University of Pennsylvania a broadly framed wrongful death lawsuit has been brought against the university, two local hospitals with which it is associated, and its private sector biotechnology collaborator, Genovo. The suit also singles out a bioethicist on the faculty who advised them as well as university trustees and specific administrators for alleged negligence and conflicts of interest. | |
| 11.10.2000 | Science | Genetic Testing: Families Sue Hospital, Scientist for Control of Canavan Gene | A lawsuit filed on 30 October in Chicago federal court is
the latest dispute in the growing controversy over who controls and who benefits from human genetics research. |
4. Social and Ethical Concerns Arising out of Biotechnology, 39. General Issues about Research |
| 11.04.2000 | Washington Post | 'Penn Settles Gene Therapy Suit' | The University of Pennsylvania announced yesterday that it had reached an out-of-court settlement with the family of Jesse Gelsinger, the Tucson teenager whose death in a gene therapy experiment 14 months ago prompted a national reassessment of protections for research volunteers. |